One-pot synthesis of 4-methylisoquinolines via a sequential Pd-catalyzed Heck reaction and intramolecular cyclization.

نویسندگان

  • Yulin Tian
  • Jianguo Qi
  • Chenbin Sun
  • Dali Yin
  • Xiaojian Wang
  • Qiong Xiao
چکیده

An efficient, one-pot synthesis of 4-methylisoquinolines via a cascade Pd-catalyzed Heck reaction, intramolecular cyclization and isomerization has been developed. This reaction has a wide range of substrates with various functional groups, and the corresponding products have been obtained in good yields.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 11 42  شماره 

صفحات  -

تاریخ انتشار 2013